He takes two steps away from me.

“Of what?” I nearly shout. I take two quick steps, catch him and reach for his arm and pull him around. “Does this have to do with her past?”

He shakes me off and starts walking away.

“Wildfire?” I say. “Is ground zero the same as wildfire?”

There’s a hitch in his step but he doesn’t turn around. Without looking back, he says, “There’s something I need to show you. Someone you need to meet.”

We walk three blocks in silence and he ascends the stairs of a boxy three-story home with an over-sized front window. He looks both ways and speaks quietly.

“Get in here if you want to see what happens when science goes wrong.”

I’m met by a hippopotamus.

In Chuck’s foyer hangs a giant stuffed hippo head with a toothy overbite, mounted on a leather backing. Chuck walks directly through the entrance and into a doorway on the left. I follow. From upstairs, I hear a voice: “Mr. Chuck?”

He presses an intercom on the wall, and says: “I’ll be up shortly. Please keep Victor entertained.”

We stand in a living room decorated in Hunter Chic. Mounted on the wall are a stuffed cheetah, a black bear, and something from the antelope/elk family. The rest of the room is modern—stylized metal coffee table, sharp-cornered couch, and, of course, a flat-panel TV big enough to watch from space.

“Is my grandmother safe?”

“I assume so.”

“Why?”

“I need more information,” he says. “What happened to her? Where? When?”

“You really don’t know.”

He purses his lips, looks me in the eye, and then glances away. He doesn’t know.

When I first met G.I. Chuck, he’d had a sty beneath his eye. Now it’s inflamed with a hordeolum, a white pimple that means his infection is intensifying but, I have to wonder, if that’s a by-product of stress taxing his immune system.

“Chuck, you’re getting no information out of me. None. Not until you explain what’s going on. You can shoot me and stuff me but no matter what you do, information is now going in a single direction in this conversation.”

“Sit,” he says. “I’ll be right back.”

“Who took my grandmother?”

“Let me get some things to show you.”

Damn it. What choice do I have?

Chuck walks out.

I see a stainless steel refrigerator built into a cabinet beneath the cheetah. “Can I grab a water?”

“Help yourself,” I hear from the other room.

I open the fridge and take a bottle of water. But I’m looking for something else—I’m not exactly sure what until I see it sitting beneath the fridge: the steel glint of a wine opener. The proverbial sharp object. I slip it into my pocket.

Chuck returns, holding a sleek, maroon-colored Dell laptop in his left hand and a small projector in his right. He opens the computer and plugs the projector into it. Onto the wall, he projects an image of a title page of a presentation. The title reads: “Human Memory Crusade.”

“Listen first, then I’ll show you the slide deck.”

I can’t believe it. In this region and era, even the dark conspiracies have a PowerPoint presentation.

“You’re theories are half right,” he begins. “You’ve missed the main point: We started trying to enhance memory.”

He explains that Biogen and Dr. Laramer teamed up to determine whether there might be a way to enhance memory capacity through heavy computer use. For Laramer, this was a cool science project; for Biogen, an opportunity to cater to 70 million baby boomers and their parents losing memories—or terrified they will.

“Great market, right? This country is obsessed with memory.”

He points out we are maniacal recorders of our own lives—photos, blogs, diaries, YouTube videos, and on and on. Memories have become a perverse way of immortalizing ourselves by looking backwards.

I have to concede this to him, but it still doesn’t all fit so neatly. “Where does the military come in?”

“I can’t talk about it.”

“Tell that to the papers after I broadcast it across the blogosphere.”

“Hear me out.”

“Khe Sahn,” I say, a seeming non sequitur.

I remember that I’d seen an ornery short man leave the dental offices wearing a Vietnam vet’s insignia. It strikes me that the military’s interest involves modifying memories of military personnel. I tell this to Chuck.

“You’re dealing with post-traumatic stress disorder,” I venture.

“Hear me out.”

He hits a button on his computer and the presentation brings up its first slide. It’s an elderly man, with thin white hair and stooped shoulders, playing on a computer. G.I. Chuck hits the button again, magnifying the image of the computer screen the old man is looking at. In the middle of the screen is a query: Tell me about your experiences in high school.

That’s not the interesting part.

What’s odd are the numerous images and statements surrounding the prompt. At the top is a ticker of information, like a news crawl on CNN. It reads: “PLAY GAMES ANYTIME YOU WANT,” and “THANKS FOR BEING PART OF THE CRUSADE.” On the right is an airplane trailing a banner that says: “Nice Chevrolet!” Filling out the screen are a half dozen multi-colored butterflies. It’s chaos—digital overload.

It helps explains Grandma’s transcripts.

“Heavy sensory input,” I say. “Big deal. We get it all the time.”

“The conventional wisdom is that we enhance our mental capacities through regular use,” he says. “That our brain is a veritable muscle that we can build through exercise.”

“That was the hope of ADAM.”

“Of what?”

“Biogen’s software: Advanced Development and Memory.”

“Right. Nicely synthesized.”

I can’t tell if he’s patronizing me.

He explains that for years, Biogen—along with every other biotech company—has been working on anti-dementia drugs. They’ve got an interesting traditional drug in the pipeline. They believed they could increase the drug’s effectiveness by stimulating the brain through computer use. If they could prove that theory, it would be an incredible scientific breakthrough, to say nothing of a multibillion-dollar entrepreneurial one.

It’s a powerful thought, but not at all inconsistent with a host of recent neurological developments.

I recently blogged about researchers at Stanford using real-time MRIs to develop new ways to treat chronic pain. In the studies, patients experiencing pain were shown images of their brains with the regions of the brain lit up that were affected—activated by heavy blood flow—during the pain episode. The researchers sought to coax patients to meditate, breathe, and use other tactics to diminish the size of the affected area.

Separately, I’ve written about research into the effects of compulsive computer use on the brain almost since my first postings. The research shows, at the least, that the heavy and regular stimulation generates neuro-chemicals linked to addiction. And, more broadly, researchers have discovered in the last few years that the brain is much more plastic than we ever previously thought.

So why not study what happens to the brain’s memory center during computer use? Why not try to stimulate neuro-chemicals that facilitate memory retention? After all, memory is an essential part of the human experience and the thing we are losing at an alarming rate.

Although I’m not buying the whole story, big parts make sense.

“What went wrong?” I ask.

Chuck brings up the next slide. It’s an image of the brain. Two small, banana-shaped regions in the center of the brain are highlighted, drawn out of proportion with the others. These are the hippocampi.

“The research team noticed that some Human Memory Crusade users were experiencing accelerated memory loss,” he says.

He hits the button again, revealing an image of a collection of cells. Above the image is a caption: Magnification, 75,000:1.

“I’m over my head here,” Chuck says. “In lay terms, these are memory cells.”

“And they were dying,” I interrupt.

“Cortisol,” he says.

“Of course.” Even though I’d guessed this earlier, I’m hit hard by the revelation.

The hyper-stimulation released cortisol.

“So the brain wasn’t strengthened but weakened,” I say.

He nods. “You understand how this works?”

“Maybe.”

“Explain it to me. I’ve heard it a dozen times, and I never can quite grasp the science.”

“What happens to you when you multitask?”

“I get a lot of shit done.”

“But at a cost.” I stand, start to pace, and think aloud.

“When you’ve got a ton of information flowing—when you’re trying to juggle e-mail, browsing, phone calls, whatever—you’re putting yourself in a highly stressful situation. Your brain is fighting to keep up.”

“How stressful can e-mail be?”

“Don’t think of it like that. Think of the computer as a virtual environment—our twenty-first-century jungle. We spend all day interacting with it. If we were in an actual jungle, it would be highly stressful if we had to face challenges from lots of different directions—lions on one side, alligators on another, hot sun, battles for food, whatever.”

“So?”

“In that environment, our adrenal glands produce brain cortisol, a lot of it. It’s a stress hormone. It helps us focus intensely for a short period so we can survive.”

“Okay, I get that analogy.”

I’m sure he’s patronizing me. But I continue hypothesizing.

“The problem is that cortisol kills memory cells.”

“Bingo.” He looks impressed.

I don’t know enough about the neuroscience to know if this is a big deal, though I sense from the violence and secrecy involved here that Biogen and Laramer have discovered something radical.

“Say something,” Chuck says.

“You’re killing my grandmother’s brain.”

He looks away.

“It’s worse than you think.”